Corona Symptoms – These Symptoms May Indicate COVID-19 – Heilpraxis

What are the symptoms of a corona infection? How do you distinguish between COVID-19, the flu and the common cold? (Image: Michael Stifter / Stock.Adobe.com)

With the increase in the number of infections, many people who experience cold symptoms wonder if it could also be so-called corona symptoms. Today, the Robert Koch Institute (RKI) reported 8,685 new infections in Germany. This is an unusually high number, as many health authorities are not releasing any current figures this weekend. 14,714 new infections were there on Saturday. A record to date.

Anyone with cold symptoms like a cough, runny nose and sore throat wonders if it could be COVID-19. The so-called corona symptoms are not very specific. So here’s a preview.

A record number of new infections

Nearly 15,000 new infections nationwide within 24 hours on Saturday – the highest value that has been reported so far. However, the RKI admits that late registrations from individual health authorities can also be included. However, the growing number of infections shows that the virus is spreading rapidly.

The SARS-CoV-2 coronavirus can cause different symptoms in everyone. Most of those affected have no symptoms, mild or moderate. However, some must be hospitalized, others must even be artificially ventilated.

Common corona symptoms

Fever, dry cough, fatigue

Less common corona symptoms

Body aches sore throat diarrhea conjunctivitis headache loss of taste or smell discoloration of fingers or toes or rash

Severe symptoms

Difficulty breathing or shortness of breath Chest pain or pressure Loss of speech or movement

Complications with COVID-19

Various complications can arise with COVID-19. Coronavirus infection can lead to pneumonia, acute respiratory distress syndrome, and inflammation of the heart, brain, or muscle tissue. According to the RKI, the risk of complications is higher in the elderly and in people with underlying illnesses. Unlike the flu, additional complications can arise. For example, blood clots and multisystem inflammation can occur. A coronavirus infection should therefore be taken very seriously.

Also read:
– Flu or COVID-19? Reliable diagnosis only through laboratory tests
– Corona: the blood type influences the risk of infection

When does the risk of complications increase?

According to the RKI, the risk of severe disease aged 50 to 60 increases with age. The average age of the deceased is 82 years old. “More than 85 percent of the deaths were 70 years and older,” according to the RKI. Various pre-existing conditions such as cardiovascular disease, diabetes, obesity, cancer, chronic lung and liver disease, and some forms of immunosuppression increase the risk of severe disease progression regardless of age.

Contact a doctor if you suspect

Only a test can reliably differentiate whether it is a cold, flu, or COVID-19. Anyone who feels the symptoms described and may even have had so-called risky contacts with suspected cases or infected people should first contact the responsible health service or the family doctor by phone. A test is then launched. If there is also shortness of breath and a high fever, an emergency doctor should be called. (Sb)

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This text conforms to the requirements of specialized medical literature, medical directives and current studies and has been verified by health professionals.

Sources:

Robert Koch Institute: Information on the detection, diagnosis and treatment of patients with COVID-19 (accessed October 14, 2020), Robert Koch Institute

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Flu or COVID-19? Reliable diagnosis only by means of a laboratory test – healing practice

Cough, mild fever, runny nose – is it a cold, the flu, or even COVID-19? Finding out is not that easy. (Image: absolutimages / stock.adobe.com)

Similar symptoms: flu or corona?

Anyone who coughs and sniffles currently often worries that they have been infected with the SARS-CoV-2 coronavirus. Such complaints also occur with other diseases. It is not easy to determine whether the symptoms are caused by COVID-19 or possibly the flu.

Persistent cough, slightly elevated temperature, runny nose – is it a cold, already the flu, or even COVID-19? Finding out is not that easy.

Clear diagnosis is not easy

With fall comes the cold, wet days – for many people associated with colds and flu-like infections, which can have a variety of triggers. According to the Robert Koch Institute (RKI), influenza viruses that cause influenza also circulate between early October and mid-May. This year, the corona pandemic is added.

A clear diagnosis of the infection present in each individual case is not so straightforward for those affected or for healthcare professionals. The symptoms are too similar: in its “Corona profile”, the RKI mentions cough (in 45% of recorded cases) and fever (38%) as the most common signs of COVID-19. Additionally, many patients reported colds (20%) and loss of smell and taste (15%).

Safety only through laboratory testing

On behalf of pharmacies, the health portal “aponet.de” compared the most common symptoms of COVID-19 with those of the flu. A sudden cough and fever as well as a general feeling of weakness are typical of both diseases. Neck aches, headaches and body aches as well as runny noses are reported to be much more frequently in patients with the flu, while loss of smell and taste is reported to occur more often in people with corona. Ultimately, however, the only way to be sure of the cause of these complaints is to take a lab test.

According to pharmacists, however, “common colds” are more easily distinguished from these two illnesses. Their typical symptoms such as sore throat, runny nose, exhaustion, and headaches usually appear gradually over several days. You feel sick, but not as completely helpless as with a real flu.

More severe courses in COVID-19

The proportion of very severe courses is significantly higher in people with corona than in those with influenza. This is the result of an ongoing RKI study. On average, COVID-19 patients stayed longer in hospital treatment and more often and longer in the intensive care unit. 22 percent of people with COVID-19, but only 14 percent of flu patients, needed to be connected to ventilators. (announcement; source: dpa)

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This text conforms to the requirements of specialized medical literature, medical directives and current studies and has been verified by health professionals.

Sources:

Robert Koch Institute (RKI): SARS-CoV-2 Profile on Coronavirus Disease 2019 (COVID-19), (accessed October 24, 2020), Robert Koch Institute (RKI)

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

The Best Masks for Sports – Healing Practice

Many sports enthusiasts also wear a mouth and nose cover on the outside to protect themselves from corona. (Image: Kzenon / stock.adobe.com)

What protective masks for training?

Although there are currently many restrictions: sport is also possible and recommended during the corona pandemic. Those who train should always protect themselves and others from infection with the SARS-CoV-2 coronavirus. It is especially important to wear a face mask. But which masks are best suited for training?

Anyone who wants to work out in the gym usually needs to wear a nose cover and mouthpiece. Even when jogging outside, many people now wear a mask to protect themselves and others from infection with SARS-CoV-2. But what should you pay attention to when choosing protective masks?

Choose the right mask

If you opt for a face mask that sits higher on your mouth and nose so you don’t reuse your mask when you breathe, infectious disease specialist Dr. Kristin Englund, in a recent article from the famous Cleveland Clinic (USA ).

Want your mask to fit properly, be comfortable and breathable, but also want a seal around your nose and mouth? Then look for a mask that fits perfectly but allows you to breathe comfortably.

Several fitness brands have released masks specifically for exercise that use a moisture-wicking material or spandex. These substances are lighter and easier to breathe. Be sure to wash your mask after every workout or use a new one.

Training becomes a little more difficult

The doctor recommends that you do not exercise with ventilated masks, because they offer no protection to anyone. Ventilated masks are designed to prevent dust particles from entering when you breathe in, but when you breathe out airborne particles and mucus particles can also escape.

Wearing a face mask will make the exercise a bit more difficult, but it can be done safely. When you exercise with your mask on, observe how you feel and look for signs of dizziness, lightheadedness, and shortness of breath.

If you experience these symptoms, you may need to change your exercise routine, at least until you are used to exercising with a face mask. People who have a high level of fitness may not feel the effects of mouth and nose protection as much as those who have just started exercising.

If you have an underlying condition, talk to your doctor before wearing a face mask during exercise, the expert concludes. (a d)

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This text conforms to the requirements of specialized medical literature, medical directives and current studies and has been verified by health professionals.

Sources:

Cleveland Clinic: What is the Best Type of Face Mask for Exercising ?, (Accessed October 25, 2020), Cleveland Clinic

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Blood type influences risk of infection – healing practice

Scientific research suggests a possible link between different blood groups and the likelihood of COVID-19 infection. (Image: Destina / stock.adobe.com)

Blood group and risk of corona disease

The individual risk of coronavirus infection can vary widely. But why are some people infected with the new type of pathogen – and others not? Blood type could play a role here, as researchers are now reporting.

As the Federal Center for Health Education (BZgA) wrote months ago on its portal “infektionsschutz.de”, several studies indicate that blood type can influence both personal risk of infection and severity of symptoms. symptoms of COVID-19. However, these scientific studies have not shown consistent results. Austrian researchers are now presenting new findings.

Comparable studies confirmed

Scientists from the University of Medicine (Med Uni) Graz are currently studying the possible link between different blood groups and the likelihood of COVID-19 infection at the University Clinic for Blood Group Serology and Transfusion Medicine. Early research results confirm comparable studies in China and Europe, according to a press release, that people with blood group 0 are less likely to contract COVID-19 than people with blood groups A, B or AB . Now the mechanism on which this observation is based needs to be investigated.

Causes that promote infection

Research is currently being carried out around the world into the causes that promote infection with SARS-CoV-2 or influence the course of COVID-19. The AB0 blood group appears to play a role here, as the results of a study in China and some European countries show. Red blood cells (erythrocytes) are ring-shaped cells that carry oxygen and carbon dioxide in the bloodstream. As explained in the communication, the “shell” of red blood cells is called the “membrane”. In this membrane there are several different carbohydrates (sugars) and proteins that give red blood cells a certain surface structure, they are also called “antigens”.

The “blood group carbohydrates” A and B are also such antigens. For the AB0 blood group, a distinction is made between the properties A, B, AB and 0 (zero). According to experts, people with blood group “0” do not have any of these blood group antigens on the surface of their red blood cells. In people with blood type “AB” both carbohydrates (A and B) are contained in the erythrocyte membrane. And with the “A” blood group only the “A” antigen is present, with the “B” blood group only the “B” antigen.

Retrospective case-control study

It is known that the sugar structures, as they are in the AB0 blood group system on the cell surface of red blood cells, but also in the tissues of the respiratory organs and the gastrointestinal tract, not only in the recognition of groups blood antibodies, but also in the recognition of microorganisms play a role. “Pathogens such as bacteria or viruses can selectively bind to the structures of blood groups and influence the colonization of affected tissues or uptake into cells,” explains Eva Maria Matzhold, study leader, molecular biologist at the University Clinic for Blood Group Serology and Transfusion Medicine, Med Uni Graz. “In our study, we are investigating whether the properties of ABO blood groups may represent a possible additional risk factor for infection and disease by COVID-19,” adds transfusion specialist Thomas Wagner.

In the first research results presented, it could already be shown that a link between the blood group and an infection with the coronavirus SARS-CoV-2 can be proven. This confirms the first indications of a study in China and a genome-wide association study (European research group GWAS COVID-19). The Med Uni Graz study is designed as a retrospective case-control study with a total of 399 people who tested positive for SARS-CoV-2 who were in hospital treatment due to COVID-19 disease.

The severity of the disease remains unchanged

“The results of our study show that people with blood group O have a statistically significantly lower probability of developing COVID-19 than people with other ABO phenotypes (blood group A, B or AB),” report the researchers . The AB blood group, on the other hand, was found to be significantly more frequently in infected and COVID-19 patients compared to the frequency of occurrence in the healthy control group.

However, the severity of the COVID-19 disease is not affected by the AB0 blood group. This means that the disease is not easier in people with blood group 0 than in people with blood type AB. An AB0 blood group determination should not currently be used as a prognostic marker for the course of COVID-19. According to the researchers, the task now is to carefully research the mechanism that plays a role in this regard. Other blood group systems are also included in the surveys, the scientists explain. (a d)

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Sources:

Medical University of Graz: COVID-19: Focus Blood, (accessed October 17, 2020), Medical University of Graz Federal Center for Health Education: Coronavirus: Questions and Answers: Course of the disease and immunity, (accessed October 17, 2020) , infektionsschutz.de

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Vitamin D and Exercise Help Fight Bone Loss – Healing Practice

Good nutrition and adequate exercise can prevent osteoporosis. (Image: Patrizia Tilly / stock.adobe.com)

Prevent osteoporosis

According to experts, osteoporosis is the most common disease of the skeletal system. The disease mainly affects the elderly (women more often than men). In Germany alone, around five to six million people are affected. Good nutrition and sufficient physical activity can prevent the disease.

Each year, more than 800,000 people in Germany are newly diagnosed with osteoporosis (also called bone loss). “The number of diseases is steadily increasing,” explains Prof. Dr. Christoph-E. Heyde, director general of the clinic and polyclinic for orthopedics, trauma surgery and plastic surgery at the University Hospital Leipzig, in a statement. “This development shows us the advantages and disadvantages of advances in medicine: on the one hand, people get older and on the other hand, it increases the risk of contracting a disease that accompanies age. Because osteoporosis particularly affects the elderly. “

Women more often affected
As the Leipzig orthopedist explains, everyone loses more and more bone mass as they age. This can cause osteoporosis. The fact that women in particular suffer from this bone loss is due to postmenopause: after menopause much less estrogen is formed, so a building block of bone formation is missing and the bones become brittle. In men, the sex hormone (here testosterone) is also important for bone metabolism. However, since there is no sudden drop in testosterone production, osteoporosis is less common in men than in women.

The disease does not cause any symptoms at first

“Osteoporosis is a creeping disease that causes no symptoms at first,” says Prof Heyde. “But it’s also dangerous. Because there are more and more bone fractures – of the vertebral bodies, the neck of the thigh or the wrist. This not only limits the mobility and independence of those affected, but can also lead to death in the event of complications. “

Before such fractures occur, those affected often notice that they become smaller and twisted. Then a doctor should be consulted, because if osteoporosis is not detected, it will progress. “A lot of things have improved in the treatment. Today, we have medical and surgical options at the highest level, the disease is no longer an immutable fate ”, underlines the doctor.

“For example, today’s drugs can not only stop bone breakdown, but also stimulate reconstruction. And with special implants that better distribute the forces acting on the bones, we can help many patients from the spine to the thigh to the forearm. “

Prevention even in old age

The orthopedist and trauma surgeon urgently advises the elderly, in particular to take preventive measures against osteoporosis. “Good muscle condition can still be achieved at age 70. And so the bones are protected and formed. So: lots of outdoor exercise. I also recommend eating a balanced diet and avoiding nicotine and too much alcohol. The level of vitamin D should also be checked by the family doctor, ”explains Professor Heyde.

According to the umbrella association of the Osteoporosis Self-Help Group (OSD), around 80% of the German population has too low a vitamin level in their blood. The main source of vitamin D is sunlight on our skin. It is therefore advisable to stay outside for about 30 minutes a day. Natural sources of food are limited. According to the OSD, larger amounts only occur in oily fish – such as salmon, eel, mackerel or herring. It may be necessary to take dietary supplements – but only on medical advice.

Calcium is also important. If you have a varied diet with balanced meat, grain products, fresh fruits and vegetables, and dairy products, you don’t need extra calcium for your bones, according to Professor Heyde. People who follow a vegan diet and do not consume dairy products should be careful, but get good calcium from fruits and vegetables, says the doctor. Soy products are also beneficial for bone metabolism. (a d)

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Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Adequate sleep may prevent severe progression of Covid-19 – Healing practice

Good sleep hygiene should be observed, especially during the corona pandemic. Because lack of sleep increases the vulnerability to infections. (Image: Damir Khabirov / stock.adobe.com)

The corona pandemic also poses a major challenge to the psyche. The huge restrictions and loss of control cause people to create and cause sleep problems for some. This has other drawbacks, as a lack of sleep increases the vulnerability to infection. Experts explain why good sleep hygiene is also a prevention against COVID-19.

Good sleep hygiene is a form of corona prevention

Sleep problems were prevalent even before the corona pandemic. In the current crisis, which poses great challenges for all of us and leads to fears – whether for health or existence – it is reasonable to assume that many more people around the world with sleep disorders have them. joined. It also increases the vulnerability to infection. To prevent illness, it is important to ensure good sleep hygiene.

Higher risk of serious illness

“A lack of sleep increases the vulnerability to infections. We know this from other viral diseases. It can also be a risk factor for more serious disease processes ”, explains Prof. Dr. Georg Nilius, director of the pulmonology clinic of the Evangelical Clinics Essen-Mitte, in a message from the German Society for Research on sleep and sleep medicine (DGSM).

Of course, this plays a role in the current coronavirus pandemic. There are professional groups, such as shift workers and those working in the medical sector, who suffer from lack of sleep more often and are therefore more vulnerable. And a lot of people don’t get enough sleep just because of their jobs. “If you can, you should get a lot of sleep!” Was the general advice of Professor Dr. Nilius, “Especially nowadays, it is worth paying special attention to good sleep hygiene and quality of sleep. It is also a kind of prevention. “

According to international studies, there are indications that patients with certain sleep disorders, especially those with sleep apnea, are at a higher risk of becoming ill or developing serious illness during the corona pandemic. . Further scientific research on the subject is needed. The DGSM is involved in an investigation into the effects of COVID-19 and lockdown on sleep in the general population. The “International COVID Sleep Study” is underway with several countries. To this end, a questionnaire is available on the home page and we warmly invite you to participate.

Sleep behavior during the corona pandemic

Current studies of sleep behavior during the corona pandemic and lockdown have found, among other things, that the gap between social jet lag and our sleep-wake biological rhythm has narrowed; In other words, to put it simply, people slept more appropriately for their (natural) genetic need for sleep. It was also found that the quality of sleep deteriorated, possibly related to the expression of anxiety, depressive moods and a lack of physical activity. Women admitted to having mental health problems more often than men; In studies, employed people most often said they slept more than before the pandemic and justified it with more flexible work models.

Positive and negative developments

Workers have faced new challenges due to COVID-19, such as the increase in the number of home offices. Christina Saalwirth, psychologist at the University of the Federal Armed Forces in Munich, examined in a study what influence stress at work, the home office, a variable start to work and well-being have on sleep in Corona time and if this is compared to the period leading up to the Corona. The pandemic has changed. All data was collected using an online questionnaire which was processed by 320 employee participants who did not work shifts (51.9 percent male, 48.1 percent female; 19 to 68 years old).

20 and 13.7% of participants said they had slept less or less time since COVID-19, while eleven and 24.7% said they had slept better or longer. The longer sleep duration of almost a quarter of those surveyed is probably due in part to the increase in homework. People who work in the home office sleep longer compared to the period before COVID-19, but also have more variable work hours, which in turn are associated with poorer quality of sleep. The changes caused by COVID-19 show both positive and negative developments in terms of sleep.

“Sleep is an important but often underestimated health factor that is influenced by the changes in daily and professional life caused by COVID-19. The home office in particular, used by more than half of the participants, conceals opportunities but also risks for our sleeping behavior, which must be investigated, ”summarizes Ms. Saalwirth’s initial findings. (a d)

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Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Reminder to drink because of glass particles – healing practice

The Kanne Brottrunk GmbH & Co. Betriebsgesellschaft KG has launched a recall for a drink because it cannot be excluded that it contains glass particles. (Image: Aleksandar Mijatovic / stock.adobe.com)

Reminder: glass particles in the drink possible

The Kanne Brottrunk GmbH & Co. Betriebsgesellschaft KG of Selm-Bork (North Rhine-Westphalia) has launched a recall for the product “Kanne Brottrunk” in a 0.75 liter glass bottle. According to the company, it cannot be excluded that there are glass particles in the drink. Consumption of the product is not recommended.

Kanne Brottrunk GmbH & Co. Betriebsgesellschaft KG from Selm-Bork in North Rhine-Westphalia calls the product “Kanne Brottrunk” in the 0.75 liter glass bottle with lot L20094, lot ID 04/03 / 2023 and one hour from 10:00 to 11:00 return.

Glass breakage following a technical defect

“When filling the product at the Selm-Bork site, glass broke due to a technical defect. The fault has already been corrected. We cannot rule out that individual glass particles ended up in bottles of this production, ”explains the company in a message published by the Federal Office for Consumer Protection and Food Safety (BVL) on its “food warning.de” portal.

According to reports, the lot was only bottled on April 6, 2020 at the Selm-Bork site and was only sold by Alnatura Germany, Alnatura Switzerland and tegut. These companies have since withdrawn the affected product from sale. Customers can return products with this Lot ID using the usual purchasing channels. The purchase price of the goods will be refunded.

Do not consume

Kanne Brottrunk GmbH & Co. Betriebsgesellschaft KG advises its customers not to consume drinks from the affected batch. Foods that may contain broken glass or broken glass should generally no longer be eaten. Because they can lead to serious mouth and throat injuries or even internal injuries. In food production, errors in manufacturing processes lead to contamination or foreign objects such as glass, aluminum or plastic residue. (a d)

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This text complies with the requirements of specialized medical literature, medical directives and ongoing studies and has been verified by healthcare professionals.

Sources:

Federal Office for Consumer Protection and Food Safety: Details of food warnings, (accessed October 25, 2020), food warning.delebensmittelwarnung.de: Message from Kanne Brottrunk GmbH & Co. Betriebsgesellschaft KG, (accessed October 25, 2020 ), food warning.de

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

Corona symptoms – These complaints point to COVID-19 – Heilpraxis

What are the symptoms of a corona infection? How do you distinguish between COVID-19, the flu and the common cold? (Image: Michael Stifter / Stock.Adobe.com)

With 14,714 new infections in 24 hours, which were reported by the Robert Koch Institute (RKI) on Saturday, the number of infections has reached the highest value since the start of the corona pandemic. Anyone with cold symptoms like a cough, runny nose and sore throat wonders if it could be COVID-19. The so-called corona symptoms are not very specific. So here’s a preview.

A record number of new infections

Almost 15,000 new infections nationwide in 24 hours – the highest value yet. However, the RKI admits that late registrations from individual health authorities can also be included. However, the growing number of infections shows that the virus is spreading rapidly.

The SARS-CoV-2 coronavirus can cause different symptoms in everyone. Most of those affected have no symptoms, mild or moderate. However, some must be hospitalized, others must even be artificially ventilated.

Common corona symptoms

Fever, dry cough, fatigue

Less common corona symptoms

Body aches sore throat diarrhea conjunctivitis headache loss of taste or smell discoloration of fingers or toes or rash

Severe symptoms

Difficulty breathing or shortness of breath Chest pain or pressure Loss of speech or movement

Complications with COVID-19

Various complications can arise with COVID-19. Coronavirus infection can lead to pneumonia, acute respiratory distress syndrome, and inflammation of the heart, brain, or muscle tissue. According to the RKI, the risk of complications is higher in the elderly and in people with underlying illnesses. Unlike the flu, additional complications can arise. For example, blood clots and multisystem inflammation can occur. A coronavirus infection should therefore be taken very seriously.

When does the risk of complications increase?

According to the RKI, the risk of severe disease aged 50 to 60 increases with age. The average age of the deceased is 82 years old. “More than 85 percent of the deaths were 70 years and older,” according to the RKI. Various pre-existing conditions such as cardiovascular disease, diabetes, obesity, cancer, chronic lung and liver disease, and some forms of immunosuppression increase the risk of severe disease progression regardless of age.

Contact a doctor if you suspect

Only a test can reliably differentiate whether it is a cold, flu, or COVID-19. Anyone who feels the symptoms described and may even have had so-called risky contacts with suspected cases or infected people should first contact the responsible health service or the family doctor by phone. A test is then launched. If there is also shortness of breath and a high fever, an emergency doctor should be called. (Sb)

Author and source information

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This text complies with the requirements of specialized medical literature, medical directives and ongoing studies and has been verified by healthcare professionals.

Sources:

Robert Koch Institute: Information on the detection, diagnosis and treatment of patients with COVID-19 (accessed October 14, 2020), Robert Koch Institute

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

New active against chronic heart failure – Heilpraxis

With a new active ingredient, chronic heart failure can be cured in the future. (Image: Rasi / stock.adobe.com)

New treatment for chronic heart failure

Chronic heart failure is a relatively widespread symptom, in which so far only symptom relief, but no treatment can be obtained. However, a new study by researchers at the Hanover Medical School (MHH) shows promising potential for so-called microRNA blockers to improve heart function.

So far there is no prospect of a cure for chronic heart failure and the disease can be fatal. However, researchers at MHH have now tested a new active ingredient that may still provide successful treatment in the chronic stage of heart failure. The results of the study were published in the specialist magazine “European Heart Journal”.

“Chronic heart failure is a serious disease in which the heart can no longer pump enough blood through the body’s circulation and the body’s cells can only provide insufficient oxygen and nutrients to the body’s cells,” the researchers explain. MHH researchers. In order to compensate for the lack of pumping power, the heart muscle pathologically grows and is thus further weakened.

New active ingredient developed

Pathological growth of myocardial cells in animals and humans is controlled by the non-coding microRNA miR132, which has led researchers to consider testing a synthetically produced counter-compound (CDR132L). Now, the team around Professor Dr. Dr. Thomas Thum and first author Dr. Sandor Batkai “has successfully demonstrated in the large animal model that the substance can block the main switch for cardiac hypertrophy and reverse it. chronic heart failure, “reports the MHH.

The active ingredient CDR132L belongs to so-called RNA medicine and is an artificially produced and precisely matched equivalent to the microRNA miR132, which is increasingly produced in the diseased heart. As an antisense oligonucleotide, it blocks the regulatory switch and thus prevents miR132 from stimulating heart muscle cells to pathological growth.

Therapeutically effective and without side effects

“In our study, we showed that CDR132L was therapeutically effective and without side effects,” says Professor Thum. According to the expert, the substance could thus create a new way not only to relieve the symptoms of heart failure, but also to cure the disease even in the chronic stage. The molecule is currently being tested in a clinical study in patients with heart failure. (fp)

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Author:

Dipl. Geogr. Fabian Peters

Sources:

Sandor Batkai, Celina Genschel, Janika Viereck, Steffen Rump, Christian Bär, Tobias Borchert, Denise Traxler, Martin Riesenhuber, Andreas Spannbauer, Dominika Lukovic, Katrin Zlabinger, Ena Hašimbegović, Christian Bär, Tobias Borchert, Denise Traxler, Martin Riesenhuber, Andreas Spannbauer, Dominika Lukovic, Katrin Zlabinger, Ena Hašimbegović, Johannes Winkler, Rita GaramvöyRoy13 WinkiJohangyLoyleri, JohannesLoyleri, Rita Garamvöy systolic and diastolic function in a large animal model of chronic heart failure; in: European Heart Journal (published October 22, 2020), academy.oup.com School of Medicine Hanover (MHH): Hope for people with chronic heart failure (published October 22, 2020), mhh.de

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.

COVID-19 Causes Many More Complications Than The Flu – Healing Practice

The impending complications are much more serious with COVID-19 than with the flu. (Image: Paulista / stock.adobe.com)

COVID-19 has far more serious consequences than the flu

COVID-19 is often compared to the flu and the severity of the illness is put into perspective. On the one hand, however, the possible consequences of the flu should in no way be underestimated, and on the other hand, a current study shows that COVID-19 causes many more complications than the flu.

With COVID-19, those affected develop many more and more serious complications than with the flu, the British Medical Journal (BMJ) reports of the results of a recent study by the US Veterans Health Administration. During hospital admissions, people with COVID-19 are also more likely to need intensive care, long hospital stays and are more likely to die from the infection.

COVID-19 is repeatedly compared to the flu, but so far there have been no reliable figures allowing a scientific comparison. In the current study, hospital treatment data for 3,948 COVID-19 cases and 5,453 influenza cases were assessed. All infections have been laboratory confirmed.

The risk of lung failure increases dramatically

The assessment showed that people with COVID-19 and influenza were mostly of a similar age (average 70 versus 69) and had almost all of the underlying illnesses (93.6% for COVID-19 and 95.1% for influenza). However, the risk of acute respiratory distress syndrome (ARDS) was almost 19 times higher with COVID-19 than with the flu.

Overall, according to the researchers, there was a higher risk of respiratory complications with COVID-19 – with twice the risk of pneumonia, 1.7 times the risk of respiratory failure, 19 times the risk of ARDS and 3.5 times the risk of pneumothorax – both compared to the flu.

People with COVID-19 have died much more often

The BMJ reports that the risk of myocarditis, deep vein thrombosis, pulmonary embolism, intracranial hemorrhage, hepatitis / acute liver failure, bacteremia and pressure ulcers was more than twice as high with COVID -19 than with the flu. Finally, hospital stays of people with COVID-19 lasted almost three times longer than those of patients with the flu, and the likelihood that they would have to be admitted to an intensive care unit was twice as high. The disease also ends fatally five times more often in people with COVID-19 than in the flu (21% died vs. 3.8%).

Overall, COVID-19 is associated with much more serious and frequent complications than with the flu. A trivialization of the disease is therefore by no means appropriate. (fp)

Author and source information

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This text complies with the requirements of specialized medical literature, medical directives and ongoing studies and has been verified by healthcare professionals.

Author:

Dipl. Geogr. Fabian Peters

Sources:

British Medical Journal (BMJ): Covid 19: Patients have many more complications than flu patients, according to US study (published October 22, 2020), BMJ Jordan Cates, Cynthia Lucero-Obusan, Rebecca M. Dahl, Patricia Schirmer , Shikha Garg, Gina Oda, Aron J. Hall, Gayle Langley, Fiona P. Havers, Mark Holodniy, Cristina V. Cardemil: Risk of Hospital Complications Associated with COVID-19 and Influenza – Veterans Health Administration, States United, October 1, 2018 – May 31, 2020; Centers for Disease Control and Prevention (published October 23, 2020), CDC

Important note:
This article is provided for informational purposes only and should not be used for self-diagnosis or self-treatment. It cannot replace a visit to the doctor.